Sex differences in urological management during spinal cord injury rehabilitation: Results from a prospective multicenter longitudinal cohort study (Record no. 1889)
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042 ## - AUTHENTICATION CODE | |
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Authentication code | dc |
100 10 - MAIN ENTRY--PERSONAL NAME | |
Personal name | Anderson, Collene E. |
Relator term | author |
9 (RLIN) | 2239 |
245 00 - TITLE STATEMENT | |
Title | Sex differences in urological management during spinal cord injury rehabilitation: Results from a prospective multicenter longitudinal cohort study |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Date of publication, distribution, etc. | 2022-10-12. |
500 ## - GENERAL NOTE | |
General note | /pmc/articles/PMC7614058/ |
500 ## - GENERAL NOTE | |
General note | /pubmed/36224336 |
520 ## - SUMMARY, ETC. | |
Summary, etc. | STUDY DESIGN: Prospective, multicenter, longitudinal cohort study. OBJECTIVES: To describe female-male differences in first-line urological management during spinal cord injury (SCI) rehabilitation. SETTING: Inpatient specialized post-acute SCI rehabilitation in Switzerland. METHODS: Data on bladder storage medication (antimuscarinic and beta-3 agonist) use, suprapubic catheter placement, demographic and SCI characteristics was collected within 40 days of SCI and at rehabilitation discharge from May 2013-September 2021. Prevalence and indicators of bladder storage medication and suprapubic catheter use at discharge were investigated with sex-stratified descriptive and logistic regression analyses. RESULTS: In 748 patients (219 females, 29%), bladder storage medication use at discharge had a prevalence of 24% (95% CI: 18-29%) for females and 30% (95% CI: 26-34%) for males and was indicated by cervical AIS grade A,B,C and traumatic SCI in both sexes. Thoracic AIS grade A,B,C SCI (males), and lumbar/sacral AIS grade A,B,C SCI (females) predicted higher odds of bladder storage medication use (SCI characteristic*sex interaction, p<0.01). Prevalence of suprapubic catheter use at discharge was 22% (95% CI: 17-28%) for females and 17% (95% CI: 14-20%) for males. Suprapubic catheter use was indicated by cervical AIS grade A,B,C SCI, and age >60 in both sexes. Females with thoracic grade A,B,C SCI tended to have higher odds of suprapubic catheter use (SCI characteristic*sex interaction, p=0.013). CONCLUSIONS: We identified sex differences in urological management especially in persons with AIS grade C or higher sub-cervical SCI. There is scope for well-powered, female-specific research in SCI in order to understand the underlying mechanisms and support patient-tailored management. |
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
Terms governing use and reproduction | |
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE | |
Terms governing use and reproduction | https://www.springernature.com/gp/open-research/policies/accepted-manuscript-termsUsers may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: https://www.springernature.com/gp/open-research/policies/accepted-manuscript-terms |
546 ## - LANGUAGE NOTE | |
Language note | en |
690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) | |
Topical term or geographic name as entry element | Article |
655 7# - INDEX TERM--GENRE/FORM | |
Genre/form data or focus term | Text |
Source of term | local |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Birkhäuser, Veronika |
Relator term | author |
9 (RLIN) | 2240 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Liechti, Martina D. |
Relator term | author |
9 (RLIN) | 2241 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Jordan, Xavier |
Relator term | author |
9 (RLIN) | 2242 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Luca, Eugenia |
Relator term | author |
9 (RLIN) | 2243 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Möhr, Sandra |
Relator term | author |
9 (RLIN) | 2244 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Pannek, Jürgen |
Relator term | author |
9 (RLIN) | 2245 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Kessler, Thomas M. |
Relator term | author |
9 (RLIN) | 2246 |
700 10 - ADDED ENTRY--PERSONAL NAME | |
Personal name | Brinkhof, Martin W.G. |
Relator term | author |
9 (RLIN) | 2247 |
786 0# - DATA SOURCE ENTRY | |
Note | Spinal Cord |
856 41 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://dx.doi.org/10.1038/s41393-022-00860-4">http://dx.doi.org/10.1038/s41393-022-00860-4</a> |
Public note | Connect to this object online. |
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