JOM KITA KE POLITEKNIK

Translating musculoskeletal bioengineering into tissue regeneration therapies (Record no. 894)

MARC details
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Personal name Khodabukus, Alastair
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9 (RLIN) 2269
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Title Translating musculoskeletal bioengineering into tissue regeneration therapies
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Date of publication, distribution, etc. 2022-10-12.
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General note /pmc/articles/PMC7614064/
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General note /pubmed/36223445
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Summary, etc. Musculoskeletal injuries and disorders are the leading cause of physical disability worldwide and a considerable socioeconomic burden. The lack of effective therapies has driven the development of novel bioengineering approaches that have recently started to gain clinical approvals. In this review, we first discuss the self-repair capacity of the musculoskeletal tissues and describe causes of musculoskeletal dysfunction. We then review the development of novel biomaterial, immunomodulatory, cellular, and gene therapies to treat musculoskeletal disorders. Lastly, we consider the recent regulatory changes and future areas of technological progress that can accelerate translation of these therapies to clinical practice.
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Language note en
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Topical term or geographic name as entry element Article
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Genre/form data or focus term Text
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Personal name Guyer, Tyler
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9 (RLIN) 2270
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Personal name Moore, Axel C.
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9 (RLIN) 2271
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Personal name Stevens, Molly M.
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Personal name Guldberg, Robert E.
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9 (RLIN) 2273
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Personal name Bursac, Nenad
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9 (RLIN) 2274
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Note Sci Transl Med
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Uniform Resource Identifier <a href="http://dx.doi.org/10.1126/scitranslmed.abn9074">http://dx.doi.org/10.1126/scitranslmed.abn9074</a>
Public note Connect to this object online.

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