Time to re-evaluate the risks and benefits of valproate and a call for action
- 2022-12.
/pmc/articles/PMC7613842/ /pubmed/35795925
Valproate is widely used in psychiatry and neurology, including off-label use. Here we consider its potential benefits and risks, particularly in women of child-bearing potential, and the evidence that clinical guidelines are adhered to. Finally, we consider the implications for clinical practice and research into its efficacy in off-label indications.