000			02593 am a22002533u 4500
042			_adc
100	1	0	_aWoody, Mary L. _eauthor _9522
700	1	0	_aTsypes, Aliona _eauthor _9523
700	1	0	_aBurkhouse, Katie L. _eauthor _9524
700	1	0	_aFeurer, Cope _eauthor _9525
700	1	0	_aChampagne, Katelynn _eauthor _9526
700	1	0	_aGibb, Brandon E. _eauthor _9527
245	0	0	_aDevelopment of Overgeneral Autobiographical Memory in Offspring of Depressed Mothers
260			_c2022.
500			_a/pmc/articles/PMC7044035/
500			_a/pubmed/31454265
520			_aOBJECTIVE: Maternal depression increases risk for offspring cognitive vulnerabilities, which may be a mechanism underlying the intergenerational transmission of depression. Little is known about how cognitive vulnerabilities, particularly memory biases, develop in offspring of depressed mothers. Understanding the etiology of memory biases may lead to novel intervention targets. Therefore, the current study examined the prospective impact of maternal depression on the development of offspring overgeneral autobiographical memory (OGM; i.e., the tendency to recall less specific memories), a cognitive vulnerability implicated in the intergenerational transmission of depression. METHOD: Participants were offspring (age 8-14; 51% daughters, 81% Caucasian) of mothers with (n = 129) or without (n = 122) a history of major depressive disorder (MDD) during the offspring's life. Mothers and offspring completed assessments every 6 months for 2 years. RESULTS: Compared to offspring of never-depressed mothers, offspring of mothers with a history of MDD recalled less specific memories in response to negative, but not positive, cue words at the initial assessment, and this bias was maintained across the two-year follow-up. For offspring of depressed, but not never-depressed, higher levels of maternal depressive symptoms at a given assessment predicted prospective decreases in the children's autobiographical memory specificity. Again, this finding was specific to negative, but not positive, cue words. CONCLUSION: These results suggest that maternal depression has both short- and long-term effects on the development of offspring OGM to negative cues, which may represent a malleable cognitive vulnerability for the intergenerational transmission of MDD that could be targeted for intervention.
540			_a
546			_aen
690			_aArticle
655	7		_aText _2local
786	0		_nJ Clin Child Adolesc Psychol
856	4	1	_uhttp://dx.doi.org/10.1080/15374416.2019.1650367 _zConnect to this object online.
999			_c1326 _d1326