000 | 02411 am a22003013u 4500 | ||
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042 | _adc | ||
100 | 1 | 0 |
_aSkou, Søren T. _eauthor _91322 |
700 | 1 | 0 |
_aMair, Frances S _eauthor _91323 |
700 | 1 | 0 |
_aFortin, Martin _eauthor _91324 |
700 | 1 | 0 |
_aGuthrie, Bruce _eauthor _91325 |
700 | 1 | 0 |
_aNunes, Bruno P. _eauthor _91326 |
700 | 1 | 0 |
_aMiranda, J. Jaime _eauthor _91327 |
700 | 1 | 0 |
_aBoyd, Cynthia _eauthor _91328 |
700 | 1 | 0 |
_aPati, Sanghamitra _eauthor _91329 |
700 | 1 | 0 |
_aMtenga, Sally _eauthor _91330 |
700 | 1 | 0 |
_aSmith, Susan M. _eauthor _91331 |
245 | 0 | 0 | _aMultimorbidity |
260 | _c2022-07-14. | ||
500 | _a/pmc/articles/PMC7613517/ | ||
500 | _a/pubmed/35835758 | ||
520 | _aMultimorbidity (≥2 co-existing conditions in an individual) is a growing global challenge with substantial impact on individuals, carers and society. It occurs a decade earlier in socioeconomically deprived communities, is associated with premature death, poorer function and quality of life, and increased health care utilization. Mechanisms underlying the development of multimorbidity are complex, interrelated and multilevel, but can be considered related to aging and underlying biological mechanisms and to broader determinants of health, e.g. socioeconomic deprivation. Little is known about prevention, but focusing on psychosocial and behavioral factors, particularly population level interventions and structural changes, is likely to be beneficial. Most clinical practice guidelines and healthcare training and delivery focuses on single diseases, leading to care that is sometimes inadequate and potentially harmful. Multimorbidity requires person-centered care, prioritizing what matters most to the individual and their carers, ensuring care that is effectively coordinated and minimally disruptive, and aligns with patient values. Interventions are likely to be complex and multifaceted. While an increasing number of studies examining multimorbidity interventions are available, there is still limited evidence to support any approach. Greater investment in multimorbidity research and training along with reconfiguration of healthcare supporting management of multimorbidity is urgently needed. | ||
540 | _a | ||
546 | _aen | ||
690 | _aArticle | ||
655 | 7 |
_aText _2local |
|
786 | 0 | _nNat Rev Dis Primers | |
856 | 4 | 1 |
_uhttp://dx.doi.org/10.1038/s41572-022-00376-4 _zConnect to this object online. |
999 |
_c1646 _d1646 |