000 01859 am a22002053u 4500
042 _adc
100 1 0 _aUbaldi, Silvia
_eauthor
_91015
700 1 0 _aFairhall, Scott L.
_eauthor
_91016
245 0 0 _afMRI response to automatic and purposeful familiar-face processing in perceptual and non-perceptual cortical regions
260 _c2021-04-01.
500 _a/pmc/articles/PMC7611704/
500 _a/pubmed/33596739
520 _aViewing the faces of familiar people selectively activates a distributed network of brain regions implicated in both the perceptual and non-perceptual processing of conspecifics. In this fMRI study, we investigate the influence of depth of famous-face processing on this network, comparing a passive incidental face-processing to a task that required the extraction of identity and biographic information. We observed that the precuneus, ventromedial prefrontal cortex (vmPFC), anterior temporal face patch (ATFP) and the amygdala exhibit a selective response even during incidental face processing. At the same time, face selectivity was enhanced in the lateral anterior temporal lobe (ATL) and the posterior superior temporal sulcus (pSTS) when identity and information extraction was required. Additionally, goal-directed identity and information extraction was associated with a recruitment of inferior frontal gyrus (IFG), while this region was deactivated during passive viewing. Collectively, these results show that components of the extended system reflect both the passive and active retrieval of person-related knowledge, and that the active access to such knowledge may potentially be mediate control circuits in the IFG.
540 _a
546 _aen
690 _aArticle
655 7 _aText
_2local
786 0 _nJ Neurophysiol
856 4 1 _uhttp://dx.doi.org/10.1152/jn.00481.2020
_zConnect to this object online.
999 _c1647
_d1647