000 03035 am a22002293u 4500
042 _adc
100 1 0 _aSpillane, Emma
_eauthor
_93167
700 1 0 _aWalker, Shawn
_eauthor
_93168
700 1 0 _aMcCourt, Christine
_eauthor
_93169
245 0 0 _aOptimal time intervals for vaginal breech births: a case-control study [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved]
260 _c2022-09-16.
500 _a/pmc/articles/PMC7614205/
500 _a/pubmed/36811097
520 _aBACKGROUND: Breech births are associated with a high rate of hypoxic injury, in part due to cord occlusion during emergence. Maximum time intervals and guidelines oriented toward earlier intervention have been proposed in a Physiological Breech Birth Algorithm. We wished to further test and refine the Algorithm for use in a clinical trial. METHODS: We conducted a retrospective case-control study in a London teaching hospital, including 15 cases and 30 controls, during the period of April 2012 to April 2020. Our sample size was powered to test the hypothesis that exceeding recommended time limits is associated with neonatal admission or death. Data collected from intrapartum care records was analysed using SPSS v26 statistical software. Variables were intervals between the stages of labour and various stages of emergence (presenting part, buttocks, pelvis, arms, head). The chi-square test and odds ratios were used to determine association between exposure to the variables of interest and composite outcome. Multiple logistic regression was used to test the predictive value of delays defined as non-adherence the Algorithm. RESULTS: Logistic regression modelling using the Algorithm time frames had an 86.8% accuracy, a sensitivity of 66.7% and a specificity of 92.3% for predicting the primary outcome. Delays between umbilicus and head >3 minutes (OR: 9.508 [95% CI: 1.390-65.046] p=0.022) and from buttocks on the perineum to head >7 minutes (OR: 6.682 [95% CI: 0.940-41.990] p=0.058) showed the most effect. Lengths of time until the first intervention were consistently longer among the cases. Delay in intervention was more common among cases than head or arm entrapment. CONCLUSION: Emergence taking longer than the limits recommended in the Physiological Breech Birth algorithm may be predictive of adverse outcomes. Some of this delay is potentially avoidable. Improved recognition of the boundaries of normality in vaginal breech births may help improve outcomes.
540 _a
540 _ahttps://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
546 _aen
690 _aArticle
655 7 _aText
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786 0 _nNIHR Open Res
856 4 1 _uhttp://dx.doi.org/10.3310/nihropenres.13297.2
_zConnect to this object online.
999 _c2248
_d2248