000 01908 am a22002413u 4500
042 _adc
100 1 0 _aGalili, Dana S
_eauthor
_92396
700 1 0 _aJefferis, Gregory SXE
_eauthor
_92397
700 1 0 _aCosta, Marta
_eauthor
_92398
245 0 0 _aConnectomics and the neural basis of behaviour
260 _c2022-12-01.
500 _a/pmc/articles/PMC7614087/
500 _a/pubmed/36113710
520 _aMethods to acquire and process synaptic-resolution electron-microscopy datasets have progressed very rapidly, allowing production and annotation of larger, more complete connectomes. More accurate neuronal matching techniques are enriching cell type data with gene expression, neuron activity, behaviour and developmental information, providing ways to test hypotheses of circuit function. In a variety of behaviours such as learned and innate olfaction, navigation and sexual behaviour, connectomics has already revealed interconnected modules with a hierarchical structure, recurrence and integration of sensory streams. Comparing individual connectomes to determine which circuit features are robust and which are variable is one key research area; new work in comparative connectomics across development, experience, sex and species will establish strong links between neuronal connectivity and brain function.
540 _a
540 _ahttps://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
540 _ahttps://creativecommons.org/licenses/by/4.0/This work is licensed under a CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/) International license.
546 _aen
690 _aArticle
655 7 _aText
_2local
786 0 _nCurr Opin Insect Sci
856 4 1 _uhttp://dx.doi.org/10.1016/j.cois.2022.100968
_zConnect to this object online.
999 _c2267
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