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245 0 0 _aAn update on the use of inositols in preventing Gestational Diabetes Mellitus (GDM) and Neural Tube Defects (NTDs)
260 _c2020-12-01.
500 _a/pmc/articles/PMC7614183/
500 _a/pubmed/32966143
520 _aINTRODUCTION: Obstetric history and maternal body composition and lifestyle may be associated with serious complications both for the mother, such as gestational diabetes mellitus (GDM), and for the fetus, including congenital malformations such as neural tube defects (NTDs). AREAS COVERED: In view of the recent knowledge, changes of nutritional and physical activity habits ameliorate glycemic control during pregnancy and in turn improve maternal and neonatal health outcomes. Recently, a series of small clinical and experimental studies indicated that supplementation with inositols, a family of insulin sensitizers, was associated with beneficial impact for both GDM and NTDs. EXPERT OPINION: Herein, we discuss the most significant scientific evidence supporting myo-inositol administration as a prophylaxis for the above-mentioned conditions.
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546 _aen
690 _aArticle
655 7 _aText
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786 0 _nExpert Opin Drug Metab Toxicol
856 4 1 _uhttp://dx.doi.org/10.1080/17425255.2020.1828344
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